Adverse Events The maximum agreed adverse dealings (grades 3/4) beside ALIMTA bounded by mixture with cisplatin in support of the apt of patients with MPM be neutropenia (24%); leukopenia (16%); anemia (6%); thrombocytopenia (5%); infectivity epigrammatic neutropenia (2%); fatigue (17%); thrombsis/embolism (6%); nausea (12%); vomiting (11%); dyspnea (11%); and strongbox headache (9%). The most common clinically to the thorn adverse events (all grades) were fatigue (80%); thrombosis/embolism (7%); nausea (84%); vomiting (58%); constipation (44%); anorexia (35%); stomatitis/pharyngitis (28%); diarrhea (26%); dyspnea (66%); chest pain (40%); and impulsive (22%).
The most common adverse events (grades 3/4) with ALIMTA for the treatment of patients with NSCLC were anemia (8%); leukopenia (5%); neutropenia (5%); thrombocytopenia (2%); infection without neutropenia (6%); fatigue (16%); thrombosis/embolism (3%); cardiac ischemia (3%);anorexia (5%); dyspnea (18%); and chest pain (7%). The most common clinically relevant adverse events (all grades) were fatigue (87%); anorexia (62%); nausea (39%); constipation (30%); vomiting (25%); diarrhea (21%); stomatitis/pharyngitis (20%); dyspnea (72%); chest pain (38%); neuropathy/sensory (29%); infection without neutropenia (23%); and rash (17%).
See abounding Warnings, Precautions, Adverse Reactions, and Dosage and Administration section in the accompanying full Prescribing Information for refuge and dose guidelines.
GEMZAR Indications GEMZAR in combination with paclitaxel be signify for the first-line treatment of patients with metastatic breast cancer after disappointment of prior anthracycline-containing adjuvant chemotherapy, unless anthracyclines were clinically contraindicated.
GEMZAR is indicated in combination with cisplatin for the first-line treatment of patients with inoperable, locally advanced (stage IIIA or IIIB), or metastatic (stage IV) non-small cell lung cancer.
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